Chronic kidney disease (CKD) is a health condition that encompasses various levels of kidney damage, ranging from a decline in function to kidney failure. Just under one million people in North Carolina have chronic kidney disease, not including those with kidney failure. The growing prevalence of CKD can be characterized as a public health threat. The NCIOM Task Force on Chronic Kidney Disease explored ways to educate the public and health care providers about CKD and developed a plan for prevention, early screening, diagnosis, and treatment of CKD and its complications for the state’s population. The findings and recommendations of the task force are presented in this report.