Healthy North Carolina 2030 (HNC 2030) identifies key public health indicators for our state. The State Health Improvement Plan has engaged statewide leaders in ongoing efforts to improve the health of North Carolinians through policies, programs, and systems related to these health indicators. One key indicator, drug overdose deaths, accelerated around the height of the COVID-19 pandemic, peaked in 2023, and then declined over the past 2 years. With the passage of the One Big Beautiful Bill Act (OBBBA) on July 4, 2025, the NCIOM is exploring possible impacts of federal legislation on substance use treatment and drug overdose deaths in the latter half of this decade.
In the wake of COVID-19, the opioid epidemic in North Carolina surged to unprecedented levels. The death rate from drug overdose more than doubled between 2018 and 2022, before entering a period of decline in 2023 (similar to national trends). As we approach the midpoint of the decade, we face even greater challenges in the effort to treat substance use disorders and prevent opioid overdose deaths.
Five years ago, Healthy North Carolina 2030 set a target to reduce age-adjusted drug overdose deaths from 20.4 per 100,000 in 2018 to 18.0 by 2030. Healthy North Carolina 2030 set this target after reviewing data across several years and forecasts based on historical data. The group chose 18.0 deaths per 100,000 people as the target for 2030, which would have been similar to the rate in 2016.
Crude overdose death rate. NC Department of Health and Human Services Division of Public Health Injury & Violence Prevention Branch. “North Carolina Overdose Epidemic Data | Division of Public Health.” North Carolina Overdose Epidemic Data. Accessed July 22, 2025. www.dph.ncdhhs.gov/ivpb-overdose-data.
North Carolina Institute of Medicine. Healthy North Carolina 2030: A Path Toward Health. Morrisville, NC: North Carolina Institute of Medicine; 2020. www.nciom.org/healthy-north-carolina-2030
A few months after Healthy North Carolina 2030 was published, the COVID-19 pandemic swept across the country, straining our health care system and exacerbating barriers to care. Drug overdose rates accelerated around the height of the COVID-19 pandemic. By 2022, the age-adjusted overdose death rate in North Carolina was 41.8 per 100,000.
Remarkably, in August 2023, the country began to experience a significant and sustained decline in overdose deaths. According to these authors, plausible explanations for the national rate decline over the past 2 years include 1) cohort effect, in which “individuals most vulnerable to overdose may have already died, shrinking the high-risk population,” 2) harm reduction, including expanded naloxone access, shifts in drug use, and changes in drug composition, and 3) reduction in opioid availability and toxicity. Despite these encouraging trends, the present overdose death rate is 25% higher than it was when the Healthy North Carolina 2030 targets were established. The most recent data for the 12 months ending in Q4, 2024 provides an age-adjusted overdose death rate of 25.7 per 100,000.
Ahmad FB, Cisewski JA. Quarterly provisional estimates for selected indicators of mortality, 2023-Quarter 4, 2024. National Center for Health Statistics. National Vital Statistics System, Vital Statistics Rapid Release Program. Accessed July 22, 2025. www.cdc.gov/nchs/nvss/vsrr/mortality-dashboard.htm#
It remains to be seen how state and federal policies will shape the trajectory of the opioid crisis and overdose deaths, but there are reasons to be optimistic for the latter half of this decade. Since Medicaid expansion began in December 2023, over 675,000 newly eligible North Carolinians have enrolled (as of August 2, 2025). Medicaid is the largest payer of behavioral health services in the United States, including substance use disorder treatments and services. The expansion increased access to treatments, medications, and coverage for emergency department visits and inpatient hospital stays. Medicaid data from 2023 showed that over half of Medicaid beneficiaries who received treatment for opioid use disorder were adults who gained coverage through Medicaid expansion.
In the next few years, we may see the impact of programs funded by the National Opioid Settlements. Between 2022 and 2038, North Carolina has the potential to receive $1.4 billion in settlement funds to address the opioid crisis. Visit the Community Opioid Resources Engine (CORE-NC) to see up-to-date information about strategy implementation from local governments and the progress that local governments have made using settlement funds. Since 2021, NCIOM has supported county and multi-sector planning around substance use disorder and overdose prevention strategies, publishing this report to assist local decision-making for opioid settlement funds.
There are also reasons to temper our expectations, as we grapple with the future impacts of the One Big Beautiful Bill Act (OBBBA, read more here and here). It is estimated that 523,506 North Carolinians will lose their health insurance received through either Medicaid or the private health insurance marketplace. Specific changes to the private health insurance marketplace include ending premium tax credits that had helped make marketplace plans more affordable, shortening enrollment periods, and requiring additional verification processes for enrollees.
Regarding the new work requirements, Medicaid expansion adults will be required to complete and document 80 hours per month of work, volunteering, or educational activities to maintain eligibility. Furthermore, eligibility checks will need to be completed every 6 months instead of every 12 months. Medicaid expansion beneficiaries may not be able to meet these requirements for a variety of reasons, such as challenges in completing and submitting documentation, unstable work and housing conditions, as well as administrative hurdles and processing delays at the state level. These new requirements may cause 271,670 North Carolinians to lose Medicaid coverage. Additionally, the administrative burden on NC Medicaid to implement these systems may impact the agency's ability provide other needed services.
A study using national data found that the rate of overdose deaths in 2020 was twice as high among Medicaid beneficiaries (54.6 per 100,000) than for the total US population (27.9 per 100,000). Medicaid beneficiaries accounted for 25% of the US population but 48% of all drug overdose deaths. Some researchers project that Medicaid cuts from the OBBBA will cause 156,000 people to lose their medications for opioid use disorder, leading to over 1,000 excess overdose deaths each year.
Medicaid cuts will force states to find ways to make up for lost federal dollars and reduce state spending, which means eliminating programs and scaling back services. In a letter addressed to the General Assembly on August 11th, Secretary Sangvai announced that the NC Department of Health and Human Services would "begin to cut $319 million from Medicaid by implementing rate reductions of 3% across all providers, as well as rate reductions of 8% or 10% for select providers, and elimination of certain services altogether – all with an effective date of October 1, 2025." Among the institutional settings to see a 10% rate reduction are acute care hospitals and psychiatric residential treatment facilities, which provide specialized care to individuals with substance use disorders.
Cuts to Medicaid would also withdraw an important source of funding that rural hospitals rely on. Over the next 10 years in North Carolina, it is estimated that the OBBBA will reduce overall Medicaid expenditures by 11.2% and hospital Medicaid expenditures by 18.9%. Seven rural hospitals in North Carolina are already at immediate risk of closure and may not survive the loss of Medicaid financing. One health policy expert predicts that the rising costs of providing care to people without insurance will lead to the closure of some safety net clinics and hospitals. For rural and low-income areas, the loss of health care facilities and critical services will create even greater barriers to receiving care.
Looking ahead, North Carolina must overcome numerous challenges to achieve the targets established in Healthy North Carolina 2030. Drug overdose deaths may continue to decline, stagnate, or reverse trends over the next 5 years. The future is uncertain, but a few things are clear. States will need to take on more responsibility to ensure access to affordable health care while using less resources. Thousands of North Carolinians will lose health insurance; many of whom have received or are currently receiving treatment for substance use disorders. The increase in the number of uninsured people who receive medical care will place a greater financial burden on health care providers.
The biggest OBBBA changes to Medicaid are scheduled to take effect on January 1, 2027 (work requirements and 6-month eligibility redeterminations). Until then, we will continue to monitor any new developments that could help policymakers chart a path forward for North Carolina.
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Written by
Patrick Y. Tang, MPH
Project Director, NCIOM
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